We can see in nxserver.log in home directory, that localnode stuck / dying when it tries to get access.
25019 25019 2022-04-05 07:44:07 676.173 NXNODE libnxhn::NXSimulateEvent(1) start.
Load failed: 5: Input/output error
Try running <code>launchctl bootstrap</code> as root for richer errors.
Can you run
ps -ef | grep nx and check if there is any nxnode process running with parameter
If there is no such process, then it probably died. This can happen when nomachine is restarted on login window or when vnc session is running.
Do you have maybe any vnc sessions on that machine?
If process died unexpectedly, there should be a core dump file or diagnostic report. Please check directories below if there is a new one related to nxnode process:
Could you also confirm that the user is logged on to his session when
nxserver --restart is executed?